OncoDB.HCC Expression View

Gene name : XPC
Ensembl ID ENSG00000154767
Description DNA-repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125). [Source:Uniprot/SWISSPROT;Acc:Q01831]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
42 percent with 2 folds change ( 4 up and 20 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene    
Display nearby genome region Chr 3 from 9161651 bp to 19195143 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 701112 -- IMAGE clone locate on exon ( tblastx )
CH2 (2.30) HK1 (-0.18) HK3 (-1.75) HK4 (-0.15) HK5 (-0.76) HK7 (1.12) HK9 (-1.48) HK11 (-0.81) HK12 (0.29) HK13 (-0.67) HK14 (-1.54) HK15 (-1.03) HK16 (-0.42) HK18 (-0.94) HK19 (0.26) HK20 (0.07) HK21 (-1.63) HK22 (-0.54) HK24 (-0.16) HK27 (-1.54) HK28 (-0.78) HK29 (-0.25) HK31 (-0.01) HK33 (0.00) HK36 (0.12) HK37 (-0.37) HK38 (-1.94) HK39 (-1.33) HK42 (-1.07) HK46 (0.80) HK47 (1.61) HK49 (-1.52) HK62 (-0.17) HK63 (-0.84) HK64 (-1.38) HK67 (0.93) HK84 (-0.74) HK85 (0.67) SF1 (-0.06) SF12 (0.26) SF15 (-0.17) SF17 (-0.72) SF18 (-1.58) SF21 (-1.22) SF22 (-1.09) SF23 (-0.22) SF32 (-1.44) SF34 (0.72) SF35 (-2.19) SF3 (0.25) SF30 (-1.56) HK2 (2.09) HK23 (-1.24) HK41 (-1.61) SF4 (-0.02) SF8 (-1.33) SF9 (-0.82)