OncoDB.HCC Expression View

Gene name : RHOC
Ensembl ID ENSG00000155366
Description Rho-related GTP-binding protein RhoC precursor (H9). [Source:Uniprot/SWISSPROT;Acc:P08134]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
28 percent with 2 folds change ( 15 up and 0 down in 52 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- RT-PCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     COSMIC    
Display nearby genome region Chr 1 from 108045251 bp to 118051579 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 195162 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.67) HK1 (0.84) HK3 (0.38) HK4 (0.17) HK5 (1.62) HK7 (2.34) HK9 (0.48) HK11 (0.21) HK12 (-0.16) HK13 (1.05) HK14 (0.86) HK15 (1.58) HK16 (1.14) HK18 (0.81) HK19 (0.45) HK20 (0.99) HK21 (0.85) HK22 (1.08) HK24 (0.57) HK27 (-0.28) HK28 (0.54) HK29 (0.46) HK31 (1.34) HK33 (0.30) HK36 (0.28) HK37 (0.00) HK38 (0.51) HK39 (0.66) HK42 (0.38) HK46 (-0.28) HK47 (-0.94) HK49 (0.21) HK62 (-0.39) HK63 (0.08) HK64 (1.59) HK67 (0.00) HK84 (0.00) HK85 (-0.81) SF1 (1.05) SF12 (3.15) SF15 (0.60) SF17 (2.09) SF18 (1.51) SF21 (0.00) SF22 (1.59) SF23 (0.67) SF32 (0.72) SF34 (0.96) SF35 (0.00) SF3 (0.34) SF30 (1.54) HK2 (-0.42) HK23 (0.76) HK41 (0.04) SF4 (0.82) SF8 (1.02) SF9 (0.45)