OncoDB.HCC Expression View

Gene name : UGT2B4
Ensembl ID ENSG00000156096
Description UDP-glucuronosyltransferase 2B4 precursor (EC 2.4.1.17) (UDPGT) (Hyodeoxycholic acid) (HLUG25) (UDPGTh-1). [Source:Uniprot/SWISSPROT;Acc:P06133]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
45 percent with 2 folds change ( 8 up and 18 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Northern    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 4 from 65380474 bp to 75396212 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 246430 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.74) HK1 (-1.15) HK3 (-1.74) HK4 (-5.17) HK5 (0.75) HK7 (-0.01) HK9 (-0.65) HK11 (-0.56) HK12 (-1.72) HK13 (-0.52) HK14 (0.37) HK15 (-2.46) HK16 (-1.05) HK18 (-1.10) HK19 (0.70) HK20 (-0.93) HK21 (-2.01) HK22 (1.62) HK24 (-0.66) HK27 (1.17) HK28 (0.80) HK29 (-0.77) HK31 (0.74) HK33 (0.29) HK36 (1.20) HK37 (-0.44) HK38 (-0.59) HK39 (-2.75) HK42 (-0.41) HK46 (1.16) HK47 (-2.37) HK49 (3.38) HK62 (-0.61) HK63 (0.72) HK64 (0.51) HK67 (-0.70) HK84 (-0.74) HK85 (0.79) SF1 (0.71) SF12 (-2.38) SF15 (-2.41) SF17 (-0.38) SF18 (-1.31) SF21 (0.20) SF22 (2.86) SF23 (-1.78) SF32 (-0.33) SF34 (1.03) SF35 (-1.81) SF3 (0.80) SF30 (5.06) HK2 (-0.87) HK23 (-1.18) HK41 (0.40) SF4 (-0.31) SF8 (-1.35) SF9 (0.26)