OncoDB.HCC Expression View

Gene name : SUPV3L1
Ensembl ID ENSG00000156502
Description suppressor of var1, 3-like 1 [Source:RefSeq_peptide;Acc:NP_003162]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
7 percent with 2 folds change ( 2 up and 2 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     PCR Array - - Kurokawa et al., J Hepatol. 39:1004 (2003)
up     Affy. Microarray - - Iizuka et al., J Cancer Res Clin Oncol 132:473 (2006)
Links Entrez Gene    
Display nearby genome region Chr 10 from 65609994 bp to 75638860 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 488157 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.81) HK1 (0.71) HK3 (-0.44) HK4 (0.03) HK5 (-0.37) HK7 (-0.84) HK9 (0.00) HK11 (-0.63) HK12 (0.74) HK13 (0.60) HK14 (-0.54) HK15 (0.72) HK16 (0.90) HK18 (-0.39) HK19 (-0.23) HK20 (-0.29) HK21 (-0.19) HK22 (-0.26) HK24 (0.14) HK27 (-0.27) HK28 (-1.06) HK29 (-1.25) HK31 (-0.14) HK33 (0.72) HK36 (0.69) HK37 (0.00) HK38 (0.69) HK39 (-0.57) HK42 (2.06) HK46 (0.03) HK47 (0.70) HK49 (-0.07) HK62 (-0.95) HK63 (-0.01) HK64 (-0.52) HK67 (0.07) HK84 (-0.10) HK85 (-0.56) SF1 (-0.94) SF12 (-0.52) SF15 (0.49) SF17 (0.01) SF18 (-0.31) SF21 (0.00) SF22 (-0.12) SF23 (0.15) SF32 (-0.34) SF34 (-0.38) SF35 (0.75) SF3 (1.29) SF30 (-0.50) HK2 (0.56) HK23 (0.13) HK41 (0.27) SF4 (-0.27) SF8 (-0.38) SF9 (-0.22)