OncoDB.HCC Expression View

Gene name : C8A
Ensembl ID ENSG00000157131
Description Complement component C8 alpha chain precursor (Complement component 8 subunit alpha). [Source:Uniprot/SWISSPROT;Acc:P07357]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
70 percent with 2 folds change ( 0 up and 31 down in 44 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 1 from 52093065 bp to 62156482 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 202682 -- IMAGE clone locate on exon ( tblastx )
CH2 (-3.12) HK1 (-0.80) HK3 (-1.60) HK4 (-4.90) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (-1.85) HK12 (-1.56) HK13 (0.00) HK14 (-3.47) HK15 (-1.88) HK16 (-1.82) HK18 (-1.75) HK19 (-1.27) HK20 (-1.57) HK21 (-1.59) HK22 (-0.10) HK24 (-0.48) HK27 (-1.40) HK28 (-0.16) HK29 (-0.85) HK31 (-0.62) HK33 (-0.19) HK36 (0.00) HK37 (-2.47) HK38 (-1.32) HK39 (-1.82) HK42 (-2.03) HK46 (-1.77) HK47 (-2.01) HK49 (-1.11) HK62 (-0.41) HK63 (-2.07) HK64 (-1.28) HK67 (-1.88) HK84 (-3.05) HK85 (0.00) SF1 (-1.56) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (0.39) SF34 (0.04) SF35 (-2.24) SF3 (-1.43) SF30 (-2.54) HK2 (-0.42) HK23 (-2.86) HK41 (-1.61) SF4 (-0.83) SF8 (-0.28) SF9 (-1.94)