OncoDB.HCC Expression View

Gene name : NRG1
Ensembl ID ENSG00000157168
Description Neuregulin-1, sensory and motor neuron-derived factor isoform. [Source:Uniprot/SWISSPROT;Acc:Q15491]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
28 percent with 2 folds change ( 6 up and 9 down in 52 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
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Display nearby genome region Chr 8 from 26617043 bp to 37741608 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 155716 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (1.01) HK3 (-0.55) HK4 (0.88) HK5 (2.04) HK7 (-2.40) HK9 (-1.44) HK11 (0.71) HK12 (-0.52) HK13 (-0.20) HK14 (-1.03) HK15 (-0.62) HK16 (0.45) HK18 (-0.17) HK19 (-1.16) HK20 (0.70) HK21 (-0.75) HK22 (-0.73) HK24 (0.38) HK27 (0.03) HK28 (0.23) HK29 (0.32) HK31 (0.64) HK33 (-0.07) HK36 (-0.44) HK37 (0.76) HK38 (1.03) HK39 (-1.62) HK42 (-1.51) HK46 (-0.01) HK47 (0.93) HK49 (-0.82) HK62 (0.00) HK63 (-0.59) HK64 (-0.81) HK67 (0.00) HK84 (0.18) HK85 (0.02) SF1 (1.73) SF12 (0.00) SF15 (0.21) SF17 (0.30) SF18 (0.68) SF21 (-4.12) SF22 (0.08) SF23 (-0.19) SF32 (1.10) SF34 (0.00) SF35 (-2.56) SF3 (-0.74) SF30 (-0.33) HK2 (0.56) HK23 (0.96) HK41 (1.52) SF4 (-2.34) SF8 (0.68) SF9 (-0.41)