OncoDB.HCC Expression View

Gene name : NRG2
Ensembl ID ENSG00000158458
Description Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)]. [Source:Uniprot/SWISSPROT;Acc:O14511]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
73 percent with 2 folds change ( 1 up and 35 down in 49 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
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Display nearby genome region Chr 5 from 134207444 bp to 144403063 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 1240116 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-1.16) HK3 (-1.40) HK4 (-1.90) HK5 (-1.07) HK7 (-1.50) HK9 (-1.76) HK11 (-1.03) HK12 (-1.38) HK13 (-1.94) HK14 (-1.46) HK15 (-0.83) HK16 (-1.05) HK18 (-2.56) HK19 (-1.47) HK20 (-2.28) HK21 (0.36) HK22 (-1.93) HK24 (-0.88) HK27 (1.08) HK28 (-1.22) HK29 (-1.64) HK31 (-1.90) HK33 (-0.85) HK36 (-1.52) HK37 (-1.13) HK38 (-2.30) HK39 (-0.44) HK42 (-0.75) HK46 (-2.56) HK47 (-2.87) HK49 (0.05) HK62 (0.00) HK63 (0.00) HK64 (-2.34) HK67 (0.00) HK84 (0.00) HK85 (-3.41) SF1 (-2.96) SF12 (-2.27) SF15 (-1.81) SF17 (-2.50) SF18 (0.00) SF21 (0.00) SF22 (-0.64) SF23 (-2.34) SF32 (-2.16) SF34 (-0.41) SF35 (0.00) SF3 (-0.39) SF30 (-1.33) HK2 (-1.59) HK23 (-1.71) HK41 (-2.39) SF4 (-0.46) SF8 (-0.73) SF9 (0.35)