OncoDB.HCC Expression View

Gene name : STC1
Ensembl ID ENSG00000159167
Description Stanniocalcin-1 precursor (STC-1). [Source:Uniprot/SWISSPROT;Acc:P52823]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
48 percent with 2 folds change ( 16 up and 4 down in 41 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 8 from 18755373 bp to 28768265 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 547247 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.87) HK3 (0.97) HK4 (2.03) HK5 (0.00) HK7 (-1.80) HK9 (0.00) HK11 (-0.14) HK12 (-0.65) HK13 (-0.76) HK14 (-0.01) HK15 (0.41) HK16 (-0.06) HK18 (-1.20) HK19 (-0.06) HK20 (0.82) HK21 (1.00) HK22 (0.12) HK24 (0.60) HK27 (0.75) HK28 (2.93) HK29 (0.00) HK31 (3.24) HK33 (2.53) HK36 (1.90) HK37 (-0.53) HK38 (2.93) HK39 (0.39) HK42 (0.27) HK46 (-1.26) HK47 (0.21) HK49 (0.09) HK62 (0.00) HK63 (-0.05) HK64 (0.00) HK67 (0.00) HK84 (0.00) HK85 (0.00) SF1 (1.45) SF12 (2.19) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (3.38) SF23 (0.00) SF32 (1.89) SF34 (0.00) SF35 (0.00) SF3 (1.99) SF30 (0.20) HK2 (2.86) HK23 (0.87) HK41 (3.42) SF4 (-1.02) SF8 (1.12) SF9 (1.60)