OncoDB.HCC Expression View

Gene name : LY6E
Ensembl ID ENSG00000160932
Description Lymphocyte antigen Ly-6E precursor (Retinoic acid-induced gene E protein) (RIG-E) (Thymic shared antigen 1) (TSA-1) (Stem cell antigen 2) (SCA-2). [Source:Uniprot/SWISSPROT;Acc:Q16553]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
60 percent with 2 folds change ( 2 up and 32 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- Northern    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 8 from 139171274 bp to 146274826 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 1470048 -- IMAGE clone locate on exon ( tblastx )
CH2 (-3.66) HK1 (0.12) HK3 (-0.94) HK4 (-3.57) HK5 (0.10) HK7 (0.00) HK9 (-3.00) HK11 (-1.97) HK12 (-1.56) HK13 (-3.02) HK14 (0.49) HK15 (-0.60) HK16 (-1.25) HK18 (0.26) HK19 (-1.18) HK20 (-3.43) HK21 (-1.47) HK22 (-3.92) HK24 (-0.74) HK27 (-1.85) HK28 (-2.52) HK29 (-2.69) HK31 (0.00) HK33 (-1.65) HK36 (-3.58) HK37 (-0.22) HK38 (0.10) HK39 (-1.87) HK42 (-3.01) HK46 (-0.52) HK47 (-4.31) HK49 (-1.25) HK62 (0.00) HK63 (3.23) HK64 (-4.03) HK67 (-1.92) HK84 (-0.13) HK85 (-4.92) SF1 (-0.48) SF12 (-0.19) SF15 (-1.16) SF17 (-2.85) SF18 (0.62) SF21 (1.49) SF22 (0.09) SF23 (-0.64) SF32 (-3.26) SF34 (-0.31) SF35 (-0.55) SF3 (-0.84) SF30 (-1.78) HK2 (-3.31) HK23 (-0.85) HK41 (-4.85) SF4 (-1.31) SF8 (-2.77) SF9 (-2.72)