OncoDB.HCC Expression View

Gene name : ALB
Ensembl ID ENSG00000163631
Description Serum albumin precursor. [Source:Uniprot/SWISSPROT;Acc:P02768]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
49 percent with 2 folds change ( 9 up and 19 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     cDNA Microarray - - Honda et al., Gastroenterology 120:955(2001)
down     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
down     cDNA Microarray - - Xu et al., Cancer Res. 61:3176 (2001)
down     PCR Array - - Kurokawa et al., J Hepatol. 39:1004 (2003)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Li et al., Mol Cell Proteomics 3:399 (2004)
down     Proteomic Analysis - - Yokoyama et al., Proteomics 4:21111 (2004)
Links Entrez Gene    
Display nearby genome region Chr 4 from 69488870 bp to 79505996 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 112397 -- IMAGE clone locate on exon ( blastn )
72969 -- IMAGE clone locate on exon ( tblastx )
292613 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.08) HK1 (-0.96) HK3 (-2.39) HK4 (-0.85) HK5 (-1.69) HK7 (1.71) HK9 (-5.36) HK11 (0.02) HK12 (-0.37) HK13 (0.86) HK14 (0.47) HK15 (-1.45) HK16 (-3.56) HK18 (-1.50) HK19 (-0.91) HK20 (-0.08) HK21 (-0.92) HK22 (1.16) HK24 (-0.21) HK27 (-5.36) HK28 (-0.55) HK29 (-0.19) HK31 (0.49) HK33 (-2.30) HK36 (1.26) HK37 (0.45) HK38 (-0.59) HK39 (-0.91) HK42 (-1.52) HK46 (-1.07) HK47 (0.33) HK49 (0.59) HK62 (-2.81) HK63 (1.15) HK64 (0.07) HK67 (-0.27) HK84 (-0.19) HK85 (1.09) SF1 (-0.03) SF12 (2.13) SF15 (-0.42) SF17 (2.82) SF18 (-1.28) SF21 (1.32) SF22 (-1.24) SF23 (-1.47) SF32 (0.51) SF34 (-0.37) SF35 (-1.92) SF3 (-0.44) SF30 (0.19) HK2 (-1.51) HK23 (-1.77) HK41 (0.26) SF4 (-2.18) SF8 (-0.99) SF9 (-1.07)