OncoDB.HCC Expression View

Gene name : TERT
Ensembl ID ENSG00000164362
Description Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (HEST2) (Telomerase-associated protein 2) (TP2). [Source:Uniprot/SWISSPROT;Acc:O14746]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
29 percent with 2 folds change ( 2 up and 3 down in 17 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- TRAP, QPCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     COSMIC    
Display nearby genome region Chr 5 from 0 bp to 6348162 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 712562 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.47) HK3 (-1.57) HK4 (0.00) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (-1.22) HK12 (-0.75) HK13 (0.00) HK14 (0.55) HK15 (0.42) HK16 (0.00) HK18 (0.00) HK19 (0.00) HK20 (0.00) HK21 (0.00) HK22 (-1.26) HK24 (-0.98) HK27 (0.00) HK28 (-0.50) HK29 (1.55) HK31 (-0.95) HK33 (-0.16) HK36 (0.00) HK37 (0.00) HK38 (0.36) HK39 (-0.14) HK42 (0.00) HK46 (0.00) HK47 (0.00) HK49 (0.00) HK62 (-0.93) HK63 (1.74) HK64 (0.00) HK67 (0.00) HK84 (0.00) HK85 (0.00) SF1 (0.00) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (0.06) SF34 (0.00) SF35 (0.00) SF3 (0.00) SF30 (0.00) HK2 (0.00) HK23 (0.00) HK41 (0.00) SF4 (0.00) SF8 (0.00) SF9 (0.00)