OncoDB.HCC Expression View

Gene name : DLC1
Ensembl ID ENSG00000164741
Description Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12). [Source:Uniprot/SWISSPROT;Acc:Q96QB1]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
2 percent with 2 folds change ( 1 up and 0 down in 50 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR, Mutation, LOH    
>> Link to terminologies used in OncoDB.HCC
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Display nearby genome region Chr 8 from 7985243 bp to 18416766 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 784151 -- IMAGE clone locate on exon ( tblastx )
869233 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.71) HK3 (0.40) HK4 (0.10) HK5 (-0.87) HK7 (0.61) HK9 (-0.25) HK11 (-0.10) HK12 (-0.14) HK13 (0.71) HK14 (-0.02) HK15 (-0.83) HK16 (-0.82) HK18 (-0.60) HK19 (0.06) HK20 (0.42) HK21 (-0.43) HK22 (0.23) HK24 (0.03) HK27 (0.17) HK28 (0.32) HK29 (0.09) HK31 (-0.25) HK33 (0.55) HK36 (0.59) HK37 (-0.12) HK38 (-0.72) HK39 (-0.63) HK42 (0.00) HK46 (0.44) HK47 (0.26) HK49 (-0.15) HK62 (0.00) HK63 (0.06) HK64 (-0.48) HK67 (0.93) HK84 (0.00) HK85 (0.55) SF1 (0.03) SF12 (0.25) SF15 (-0.15) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (-0.31) SF23 (0.47) SF32 (-0.21) SF34 (0.47) SF35 (0.43) SF3 (-0.48) SF30 (0.63) HK2 (-0.48) HK23 (1.25) HK41 (0.82) SF4 (-0.09) SF8 (-0.42) SF9 (-0.57)