OncoDB.HCC Expression View

Gene name : AQP3
Ensembl ID ENSG00000165272
Description Aquaporin-3 (AQP-3). [Source:Uniprot/SWISSPROT;Acc:Q92482]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
58 percent with 2 folds change ( 1 up and 31 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     cDNA Microarray - - Iizuka et al., Oncogene 22:3007 (2003)
down     PCR Array - - Kurokawa et al., J Hepatol. 39:1004 (2003)
down     Affy. Microarray - - Iizuka et al., J Cancer Res Clin Oncol 132:473 (2006)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 9 from 28431152 bp to 38437609 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 196005 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.77) HK1 (-0.70) HK3 (-1.42) HK4 (-2.67) HK5 (-0.89) HK7 (1.83) HK9 (-0.54) HK11 (-0.36) HK12 (-0.18) HK13 (-1.42) HK14 (-0.72) HK15 (-1.91) HK16 (0.00) HK18 (-0.20) HK19 (-0.21) HK20 (-2.55) HK21 (-1.21) HK22 (-0.62) HK24 (-0.91) HK27 (-0.88) HK28 (-1.78) HK29 (-1.58) HK31 (-0.64) HK33 (-0.79) HK36 (-1.45) HK37 (-1.93) HK38 (-2.76) HK39 (0.00) HK42 (-1.32) HK46 (-2.85) HK47 (-0.55) HK49 (-1.72) HK62 (-1.28) HK63 (-1.17) HK64 (-2.65) HK67 (0.26) HK84 (-3.22) HK85 (0.18) SF1 (-1.48) SF12 (-2.39) SF15 (-1.34) SF17 (0.24) SF18 (-2.53) SF21 (-0.01) SF22 (-1.93) SF23 (-3.33) SF32 (-2.87) SF34 (-0.44) SF35 (-1.45) SF3 (-1.67) SF30 (0.03) HK2 (-0.24) HK23 (-1.59) HK41 (-1.31) SF4 (-1.03) SF8 (-0.28) SF9 (-1.16)