OncoDB.HCC Expression View

Gene name : RET
Ensembl ID ENSG00000165731
Description Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret). [Source:Uniprot/SWISSPROT;Acc:P07949]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
21 percent with 2 folds change ( 1 up and 11 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     COSMIC    
Display nearby genome region Chr 10 from 37892528 bp to 47945805 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 160664 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.37) HK1 (-0.18) HK3 (-1.16) HK4 (-1.08) HK5 (-0.01) HK7 (-0.21) HK9 (-0.23) HK11 (-0.63) HK12 (-0.16) HK13 (-0.41) HK14 (-0.20) HK15 (-0.15) HK16 (-0.67) HK18 (0.09) HK19 (0.02) HK20 (-0.36) HK21 (0.31) HK22 (-0.24) HK24 (-0.56) HK27 (-0.21) HK28 (-0.40) HK29 (0.11) HK31 (-1.12) HK33 (-1.27) HK36 (1.34) HK37 (-1.64) HK38 (-0.53) HK39 (-0.59) HK42 (-0.91) HK46 (-0.36) HK47 (0.00) HK49 (0.48) HK62 (-0.66) HK63 (-1.01) HK64 (-0.80) HK67 (-0.86) HK84 (-1.64) HK85 (-0.88) SF1 (-0.77) SF12 (-0.21) SF15 (-0.38) SF17 (-0.01) SF18 (0.00) SF21 (0.25) SF22 (-0.05) SF23 (-0.47) SF32 (-0.79) SF34 (-0.18) SF35 (-1.13) SF3 (-0.77) SF30 (-1.43) HK2 (-0.09) HK23 (-1.28) HK41 (-0.72) SF4 (-0.12) SF8 (0.10) SF9 (-0.50)