OncoDB.HCC Expression View

Gene name : TPTE
Ensembl ID ENSG00000166157
Description Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5). [Source:Uniprot/SWISSPROT;Acc:P56180]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
34 percent with 2 folds change ( 12 up and 3 down in 44 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- RT-PCR    
>> Link to terminologies used in OncoDB.HCC
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Display nearby genome region Chr 21 from 4928081 bp to 15012791 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 178268 -- IMAGE clone locate on exon ( blastn )
782145 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.10) HK3 (-0.38) HK4 (5.44) HK5 (-0.88) HK7 (0.00) HK9 (0.52) HK11 (-0.45) HK12 (-3.47) HK13 (1.24) HK14 (1.41) HK15 (-0.91) HK16 (-1.77) HK18 (0.74) HK19 (-0.17) HK20 (0.71) HK21 (1.22) HK22 (-0.04) HK24 (0.54) HK27 (0.30) HK28 (0.65) HK29 (-1.13) HK31 (2.36) HK33 (0.00) HK36 (0.00) HK37 (-0.28) HK38 (0.49) HK39 (0.63) HK42 (1.46) HK46 (-0.18) HK47 (0.00) HK49 (0.00) HK62 (0.00) HK63 (0.00) HK64 (0.00) HK67 (1.98) HK84 (0.00) HK85 (0.00) SF1 (3.18) SF12 (3.42) SF15 (0.00) SF17 (-0.44) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (0.54) SF34 (-0.88) SF35 (-0.06) SF3 (1.21) SF30 (1.67) HK2 (-0.31) HK23 (-0.22) HK41 (0.79) SF4 (-0.26) SF8 (-0.32) SF9 (1.49)