OncoDB.HCC Expression View

Gene name : CYB5A
Ensembl ID ENSG00000166347
Description Cytochrome b5. [Source:Uniprot/SWISSPROT;Acc:P00167]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
29 percent with 2 folds change ( 3 up and 14 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
down     Proteomic Analysis - - Blanc et al., Proteomics 5:37788 (2005)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 18 from 65071508 bp to 75110201 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 196189 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.36) HK1 (-0.33) HK3 (-1.02) HK4 (0.13) HK5 (-0.77) HK7 (-0.57) HK9 (-0.82) HK11 (0.48) HK12 (-0.84) HK13 (0.94) HK14 (-0.74) HK15 (-1.37) HK16 (0.76) HK18 (-0.13) HK19 (-0.49) HK20 (-0.39) HK21 (-1.39) HK22 (1.25) HK24 (-0.35) HK27 (-0.86) HK28 (1.03) HK29 (0.19) HK31 (-0.13) HK33 (0.83) HK36 (0.37) HK37 (0.10) HK38 (-0.88) HK39 (-1.94) HK42 (-2.21) HK46 (-0.26) HK47 (-0.51) HK49 (0.01) HK62 (-0.96) HK63 (0.33) HK64 (0.47) HK67 (0.19) HK84 (-0.84) HK85 (0.28) SF1 (-0.78) SF12 (-1.61) SF15 (-0.91) SF17 (-0.31) SF18 (-1.74) SF21 (-1.11) SF22 (2.12) SF23 (-0.42) SF32 (0.00) SF34 (0.13) SF35 (-2.12) SF3 (0.02) SF30 (-4.00) HK2 (-0.81) HK23 (-2.02) HK41 (-0.02) SF4 (-1.29) SF8 (-1.12) SF9 (-2.15)