OncoDB.HCC Expression View

Gene name : SERPINF2
Ensembl ID ENSG00000167711
Description Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP). [Source:Uniprot/SWISSPROT;Acc:P08697]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
47 percent with 2 folds change ( 8 up and 19 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 17 from 0 bp to 6605310 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 82195 -- IMAGE clone locate on exon ( tblastx )
1554355 -- IMAGE clone locate on exon ( tblastx )
CH2 (5.00) HK1 (-0.88) HK3 (-1.88) HK4 (-0.84) HK5 (-0.59) HK7 (2.52) HK9 (0.40) HK11 (-1.45) HK12 (-0.21) HK13 (0.78) HK14 (-1.16) HK15 (-0.29) HK16 (-1.18) HK18 (-1.23) HK19 (-1.12) HK20 (0.09) HK21 (-1.80) HK22 (-0.76) HK24 (-0.55) HK27 (-0.84) HK28 (-1.27) HK29 (0.58) HK31 (1.11) HK33 (-1.10) HK36 (0.44) HK37 (0.59) HK38 (-0.08) HK39 (-1.68) HK42 (-0.27) HK46 (-0.77) HK47 (-1.06) HK49 (-0.45) HK62 (-2.14) HK63 (0.11) HK64 (2.20) HK67 (0.13) HK84 (0.26) HK85 (-0.34) SF1 (0.15) SF12 (0.35) SF15 (1.06) SF17 (0.67) SF18 (0.84) SF21 (1.24) SF22 (-1.89) SF23 (-1.02) SF32 (1.02) SF34 (-0.12) SF35 (-2.61) SF3 (-1.17) SF30 (-2.64) HK2 (-0.28) HK23 (0.27) HK41 (-3.72) SF4 (-0.68) SF8 (1.19) SF9 (-1.53)