OncoDB.HCC Expression View

Gene name : PRDX2
Ensembl ID ENSG00000167815
Description Peroxiredoxin-2 (EC 1.11.1.15) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thiol-specific antioxidant protein) (TSA) (PRP) (Natural killer cell-enhancing factor B) (NKEF-B). [Source:Uniprot/SWISSPROT;Acc:P32119]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
10 percent with 2 folds change ( 6 up and 0 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- IHC, Western    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene    
Display nearby genome region Chr 19 from 7768635 bp to 17773694 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 212165 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.07) HK1 (-0.25) HK3 (0.26) HK4 (0.82) HK5 (-0.09) HK7 (0.21) HK9 (0.00) HK11 (0.69) HK12 (0.33) HK13 (0.90) HK14 (1.18) HK15 (0.39) HK16 (0.52) HK18 (-0.10) HK19 (0.24) HK20 (0.94) HK21 (-0.30) HK22 (1.99) HK24 (0.20) HK27 (-0.38) HK28 (0.41) HK29 (-0.40) HK31 (0.44) HK33 (0.35) HK36 (-0.15) HK37 (0.84) HK38 (0.53) HK39 (0.42) HK42 (0.48) HK46 (-0.23) HK47 (0.39) HK49 (0.45) HK62 (0.00) HK63 (0.60) HK64 (0.48) HK67 (-0.64) HK84 (1.82) HK85 (0.91) SF1 (0.61) SF12 (0.71) SF15 (1.88) SF17 (0.52) SF18 (-0.74) SF21 (-0.73) SF22 (0.67) SF23 (-0.14) SF32 (1.23) SF34 (0.97) SF35 (0.22) SF3 (-0.40) SF30 (0.90) HK2 (-0.16) HK23 (0.58) HK41 (1.08) SF4 (0.83) SF8 (0.36) SF9 (0.53)