OncoDB.HCC Expression View

Gene name : EFNA1
Ensembl ID ENSG00000169242
Description Ephrin-A1 precursor (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor, alpha-induced protein 4). [Source:Uniprot/SWISSPROT;Acc:P20827]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
35 percent with 2 folds change ( 17 up and 2 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Northern    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 1 from 148366560 bp to 158373957 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 1474684 -- IMAGE clone locate on exon ( blastn )
CH2 (1.48) HK1 (0.73) HK3 (1.24) HK4 (0.16) HK5 (0.64) HK7 (-0.33) HK9 (0.00) HK11 (1.22) HK12 (1.25) HK13 (1.07) HK14 (0.45) HK15 (0.26) HK16 (0.31) HK18 (-0.93) HK19 (-0.70) HK20 (-0.83) HK21 (0.30) HK22 (0.85) HK24 (-0.61) HK27 (0.89) HK28 (-1.02) HK29 (-0.36) HK31 (-0.01) HK33 (-0.75) HK36 (1.01) HK37 (0.79) HK38 (2.97) HK39 (1.27) HK42 (-0.11) HK46 (0.62) HK47 (0.17) HK49 (1.04) HK62 (0.75) HK63 (0.86) HK64 (-0.78) HK67 (1.90) HK84 (0.04) HK85 (0.73) SF1 (2.25) SF12 (1.62) SF15 (2.37) SF17 (0.22) SF18 (1.12) SF21 (0.00) SF22 (2.30) SF23 (0.61) SF32 (0.34) SF34 (0.39) SF35 (-1.55) SF3 (0.77) SF30 (2.51) HK2 (0.35) HK23 (0.40) HK41 (1.95) SF4 (0.00) SF8 (0.65) SF9 (-0.98)