OncoDB.HCC Expression View

Gene name : GJB1
Ensembl ID ENSG00000169562
Description Gap junction beta-1 protein (Connexin-32) (Cx32) (GAP junction 28 kDa liver protein). [Source:Uniprot/SWISSPROT;Acc:P08034]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
30 percent with 2 folds change ( 9 up and 8 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- IHC    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr X from 65351769 bp to 75362091 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 288663 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.16) HK1 (-0.36) HK3 (-0.82) HK4 (0.56) HK5 (0.53) HK7 (2.00) HK9 (0.00) HK11 (0.79) HK12 (0.61) HK13 (0.78) HK14 (-0.32) HK15 (-0.56) HK16 (0.67) HK18 (-0.76) HK19 (-0.05) HK20 (1.22) HK21 (-1.42) HK22 (0.49) HK24 (0.91) HK27 (-2.15) HK28 (0.28) HK29 (0.76) HK31 (0.49) HK33 (0.22) HK36 (0.25) HK37 (0.84) HK38 (0.79) HK39 (-1.22) HK42 (-0.58) HK46 (0.73) HK47 (-3.45) HK49 (-0.14) HK62 (-1.17) HK63 (0.27) HK64 (1.80) HK67 (0.96) HK84 (0.42) HK85 (0.45) SF1 (2.11) SF12 (0.04) SF15 (0.06) SF17 (1.87) SF18 (0.00) SF21 (4.14) SF22 (-0.64) SF23 (-0.05) SF32 (1.63) SF34 (3.24) SF35 (-2.60) SF3 (-0.19) SF30 (-2.18) HK2 (-0.63) HK23 (-0.15) HK41 (0.48) SF4 (1.11) SF8 (0.73) SF9 (-2.13)