OncoDB.HCC Expression View

Gene name : UGP2
Ensembl ID ENSG00000169764
Description UTP--glucose-1-phosphate uridylyltransferase 2 (EC 2.7.7.9) (UDP- glucose pyrophosphorylase 2) (UDPGP 2) (UGPase 2). [Source:Uniprot/SWISSPROT;Acc:Q16851]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
45 percent with 2 folds change ( 2 up and 24 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     cDNA Microarray - - Delpuech et al., Oncogene 21:2926 (2002)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 2 from 58922518 bp to 68972196 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 486436 -- IMAGE clone locate on exon ( tblastx )
488888 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.62) HK1 (-0.30) HK3 (-1.34) HK4 (-1.11) HK5 (-0.93) HK7 (0.33) HK9 (-0.70) HK11 (-1.35) HK12 (-0.50) HK13 (0.16) HK14 (-1.50) HK15 (-1.25) HK16 (-1.27) HK18 (-1.79) HK19 (-0.51) HK20 (0.35) HK21 (-1.52) HK22 (0.85) HK24 (-0.49) HK27 (-1.37) HK28 (1.18) HK29 (0.60) HK31 (0.84) HK33 (0.64) HK36 (-0.00) HK37 (-1.78) HK38 (-1.23) HK39 (-0.98) HK42 (-0.67) HK46 (-1.12) HK47 (-0.90) HK49 (0.29) HK62 (-0.51) HK63 (-0.22) HK64 (0.27) HK67 (-0.12) HK84 (-1.44) HK85 (-0.93) SF1 (-0.91) SF12 (-2.08) SF15 (-1.74) SF17 (-1.77) SF18 (-1.07) SF21 (-0.18) SF22 (-2.71) SF23 (-0.14) SF32 (1.49) SF34 (-0.03) SF35 (-1.26) SF3 (0.04) SF30 (-2.64) HK2 (-1.28) HK23 (-1.00) HK41 (-0.74) SF4 (-0.83) SF8 (-0.68) SF9 (-2.90)