OncoDB.HCC Expression View

Gene name : ROBO1
Ensembl ID ENSG00000169855
Description Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty). [Source:Uniprot/SWISSPROT;Acc:Q9Y6N7]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
60 percent with 2 folds change ( 21 up and 2 down in 38 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 3 from 73729080 bp to 84721751 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 595162 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (1.97) HK3 (0.44) HK4 (3.65) HK5 (2.27) HK7 (-0.08) HK9 (-0.47) HK11 (2.57) HK12 (2.61) HK13 (0.90) HK14 (-0.43) HK15 (1.52) HK16 (1.61) HK18 (1.15) HK19 (2.18) HK20 (2.76) HK21 (1.04) HK22 (0.28) HK24 (2.75) HK27 (0.16) HK28 (0.40) HK29 (0.00) HK31 (0.00) HK33 (0.00) HK36 (0.00) HK37 (0.00) HK38 (0.89) HK39 (0.93) HK42 (0.00) HK46 (2.17) HK47 (3.15) HK49 (3.15) HK62 (0.01) HK63 (0.40) HK64 (0.00) HK67 (0.00) HK84 (0.00) HK85 (0.00) SF1 (2.59) SF12 (0.00) SF15 (2.54) SF17 (-3.85) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (-0.41) SF32 (-2.01) SF34 (1.07) SF35 (0.00) SF3 (0.00) SF30 (0.00) HK2 (3.64) HK23 (3.68) HK41 (0.00) SF4 (0.37) SF8 (0.88) SF9 (2.91)