OncoDB.HCC Expression View

Gene name : FOS
Ensembl ID ENSG00000170345
Description Proto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7). [Source:Uniprot/SWISSPROT;Acc:P01100]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
78 percent with 2 folds change ( 1 up and 44 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     PCR Array - - Kurokawa et al., J Hepatol. 39:1004 (2003)
down     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 14 from 69815284 bp to 79818685 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 273555 -- IMAGE clone locate on exon ( blastn )
26474 -- IMAGE clone locate on exon ( tblastx )
811015 -- IMAGE clone locate on exon ( tblastx )
CH2 (-3.86) HK1 (-1.46) HK3 (-2.97) HK4 (-3.91) HK5 (-1.45) HK7 (-1.69) HK9 (-0.61) HK11 (-2.13) HK12 (-1.50) HK13 (-2.47) HK14 (-2.58) HK15 (-2.31) HK16 (-1.72) HK18 (-1.33) HK19 (-2.55) HK20 (-1.94) HK21 (-0.30) HK22 (-1.47) HK24 (-2.69) HK27 (-1.65) HK28 (-2.68) HK29 (0.81) HK31 (-2.42) HK33 (-1.06) HK36 (-0.10) HK37 (-3.39) HK38 (-2.17) HK39 (-0.40) HK42 (-2.30) HK46 (-1.38) HK47 (-4.16) HK49 (-1.21) HK62 (-0.59) HK63 (-3.10) HK64 (-3.69) HK67 (-2.89) HK84 (-0.83) HK85 (0.42) SF1 (-2.00) SF12 (-4.19) SF15 (0.04) SF17 (-3.47) SF18 (-1.87) SF21 (-0.58) SF22 (-1.82) SF23 (-2.32) SF32 (-2.35) SF34 (1.19) SF35 (-2.33) SF3 (-1.79) SF30 (-2.43) HK2 (-2.38) HK23 (-3.15) HK41 (-2.99) SF4 (-0.66) SF8 (-1.56) SF9 (-0.91)