OncoDB.HCC Expression View

Gene name : MTSS1
Ensembl ID ENSG00000170873
Description Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1). [Source:Uniprot/SWISSPROT;Acc:O43312]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
28 percent with 2 folds change ( 14 up and 2 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Northern    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 8 from 120632212 bp to 130809840 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 300012 -- IMAGE clone locate on exon ( tblastx )
455123 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.21) HK1 (0.18) HK3 (0.96) HK4 (0.40) HK5 (1.06) HK7 (-0.30) HK9 (0.78) HK11 (0.47) HK12 (-0.08) HK13 (1.39) HK14 (-0.21) HK15 (-0.20) HK16 (0.00) HK18 (0.33) HK19 (0.06) HK20 (0.01) HK21 (-1.73) HK22 (0.59) HK24 (0.96) HK27 (0.28) HK28 (1.04) HK29 (0.28) HK31 (1.11) HK33 (1.29) HK36 (-0.23) HK37 (1.37) HK38 (0.10) HK39 (-0.70) HK42 (0.55) HK46 (0.25) HK47 (1.15) HK49 (0.68) HK62 (0.54) HK63 (0.18) HK64 (-0.20) HK67 (1.21) HK84 (0.87) HK85 (0.45) SF1 (3.03) SF12 (0.54) SF15 (2.49) SF17 (1.23) SF18 (2.28) SF21 (0.30) SF22 (0.39) SF23 (-0.29) SF32 (1.03) SF34 (0.60) SF35 (-1.47) SF3 (0.29) SF30 (-0.39) HK2 (-0.12) HK23 (-0.03) HK41 (1.14) SF4 (-0.78) SF8 (0.23) SF9 (-0.75)