OncoDB.HCC Expression View

Gene name : FGG
Ensembl ID ENSG00000171557
Description Fibrinogen gamma chain precursor. [Source:Uniprot/SWISSPROT;Acc:P02679]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
52 percent with 2 folds change ( 5 up and 19 down in 46 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Xu et al., Cancer Res. 61:3176 (2001)
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     PCR Array - - Kurokawa et al., J Hepatol. 39:1004 (2003)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Li et al., Mol Cell Proteomics 3:399 (2004)
up     Proteomic Analysis - - Liang et al., Proteomics 5:2258 (2005)
Links Entrez Gene    
Display nearby genome region Chr 4 from 150744739 bp to 160753352 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 119882 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.69) HK1 (-0.31) HK3 (-1.41) HK4 (1.01) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (-0.78) HK12 (-0.50) HK13 (1.28) HK14 (-2.09) HK15 (-1.09) HK16 (-1.14) HK18 (-1.04) HK19 (-2.33) HK20 (-0.96) HK21 (-0.67) HK22 (1.82) HK24 (-0.60) HK27 (-0.46) HK28 (-0.04) HK29 (-2.30) HK31 (-0.89) HK33 (-2.05) HK36 (0.17) HK37 (0.27) HK38 (1.65) HK39 (-1.86) HK42 (-4.12) HK46 (-1.48) HK47 (1.55) HK49 (-0.37) HK62 (-2.80) HK63 (-0.98) HK64 (-0.72) HK67 (-0.55) HK84 (0.00) HK85 (0.67) SF1 (0.12) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (-1.31) SF34 (-0.82) SF35 (-2.68) SF3 (-0.86) SF30 (-0.44) HK2 (-4.25) HK23 (-2.61) HK41 (-2.28) SF4 (-0.30) SF8 (-0.95) SF9 (-2.88)