OncoDB.HCC Expression View

Gene name : FGA
Ensembl ID ENSG00000171560
Description Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A]. [Source:Uniprot/SWISSPROT;Acc:P02671]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
38 percent with 2 folds change ( 5 up and 17 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Li et al., Mol Cell Proteomics 3:399 (2004)
down     Proteomic Analysis - - Li et al., Proteomics 5:1125 (2005)
Links Entrez Gene    
Display nearby genome region Chr 4 from 150723730 bp to 160731347 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 1469138 -- IMAGE clone locate on exon ( blastn )
429555 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.79) HK1 (-0.14) HK3 (-1.25) HK4 (0.91) HK5 (-0.83) HK7 (-0.43) HK9 (-1.09) HK11 (0.01) HK12 (-0.07) HK13 (1.24) HK14 (-2.47) HK15 (-0.85) HK16 (-1.51) HK18 (-0.69) HK19 (-1.44) HK20 (-0.42) HK21 (-0.52) HK22 (1.74) HK24 (-0.29) HK27 (-1.55) HK28 (-0.11) HK29 (-2.60) HK31 (0.10) HK33 (-0.35) HK36 (0.51) HK37 (-0.25) HK38 (1.45) HK39 (-1.55) HK42 (-4.32) HK46 (-0.35) HK47 (-0.16) HK49 (0.95) HK62 (-1.35) HK63 (-1.25) HK64 (1.16) HK67 (-0.37) HK84 (-0.90) HK85 (0.04) SF1 (0.19) SF12 (-1.99) SF15 (1.83) SF17 (0.26) SF18 (-0.77) SF21 (0.53) SF22 (-0.24) SF23 (-0.84) SF32 (0.05) SF34 (-0.77) SF35 (-3.05) SF3 (-0.16) SF30 (-0.24) HK2 (-2.63) HK23 (-1.67) HK41 (-1.63) SF4 (0.34) SF8 (-0.11) SF9 (-1.60)