OncoDB.HCC Expression View

Gene name : AQP4
Ensembl ID ENSG00000171885
Description Aquaporin-4 (AQP-4) (WCH4) (Mercurial-insensitive water channel) (MIWC). [Source:Uniprot/SWISSPROT;Acc:P55087]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
85 percent with 2 folds change ( 1 up and 46 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 18 from 17686008 bp to 27699714 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 46376 -- IMAGE clone locate on exon ( tblastx )
279172 -- IMAGE clone locate on exon ( tblastx )
CH2 (-2.96) HK1 (-3.36) HK3 (-2.93) HK4 (-7.83) HK5 (-5.36) HK7 (-6.36) HK9 (-6.19) HK11 (-3.90) HK12 (-3.42) HK13 (-1.95) HK14 (-4.35) HK15 (-2.78) HK16 (-2.54) HK18 (-3.35) HK19 (-3.27) HK20 (-3.43) HK21 (-0.79) HK22 (-0.72) HK24 (-3.42) HK27 (-3.08) HK28 (-0.64) HK29 (-0.60) HK31 (-5.07) HK33 (-4.08) HK36 (-2.13) HK37 (-7.84) HK38 (-1.34) HK39 (-5.67) HK42 (-2.91) HK46 (-5.71) HK47 (-5.10) HK49 (-8.64) HK62 (-1.00) HK63 (-2.72) HK64 (0.00) HK67 (-3.89) HK84 (0.15) HK85 (-4.39) SF1 (-2.09) SF12 (-6.28) SF15 (-0.00) SF17 (-3.83) SF18 (-4.14) SF21 (-3.55) SF22 (0.00) SF23 (1.36) SF32 (-3.47) SF34 (-3.92) SF35 (-3.88) SF3 (-0.79) SF30 (-5.19) HK2 (-3.49) HK23 (-1.79) HK41 (-4.05) SF4 (-3.74) SF8 (-2.18) SF9 (-0.15)