OncoDB.HCC Expression View

Gene name : SMAD2
Ensembl ID ENSG00000175387
Description Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1) (hSMAD2). [Source:Uniprot/SWISSPROT;Acc:Q15796]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
7 percent with 2 folds change ( 4 up and 0 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence mutation     Method -- Mutation    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 18 from 38618435 bp to 48711221 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 280356 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.95) HK1 (0.65) HK3 (0.47) HK4 (0.89) HK5 (0.62) HK7 (-0.19) HK9 (-0.83) HK11 (0.31) HK12 (-0.95) HK13 (0.52) HK14 (0.66) HK15 (0.84) HK16 (-0.40) HK18 (0.70) HK19 (0.24) HK20 (0.76) HK21 (0.88) HK22 (0.12) HK24 (1.01) HK27 (0.58) HK28 (0.69) HK29 (0.93) HK31 (0.69) HK33 (0.80) HK36 (1.35) HK37 (0.00) HK38 (0.70) HK39 (-0.42) HK42 (0.87) HK46 (-0.39) HK47 (1.00) HK49 (1.94) HK62 (0.12) HK63 (0.73) HK64 (1.67) HK67 (0.38) HK84 (-0.83) HK85 (-0.31) SF1 (0.34) SF12 (0.37) SF15 (0.39) SF17 (0.41) SF18 (0.69) SF21 (-0.24) SF22 (0.27) SF23 (-0.10) SF32 (0.24) SF34 (0.62) SF35 (0.51) SF3 (0.66) SF30 (0.57) HK2 (-0.22) HK23 (0.55) HK41 (0.61) SF4 (0.42) SF8 (0.41) SF9 (0.42)