OncoDB.HCC Expression View

Gene name : SPRYD4
Ensembl ID ENSG00000176422
Description SPRY domain-containing protein 4. [Source:Uniprot/SWISSPROT;Acc:Q8WW59]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
44 percent with 2 folds change ( 0 up and 25 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Li et al., Proteomics 5:1125 (2005)
down     Proteomic Analysis - - Blanc et al., Proteomics 5:37788 (2005)
Links Entrez Gene    
Display nearby genome region Chr 12 from 50148618 bp to 60151030 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 809829 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.62) HK1 (-2.07) HK3 (-0.56) HK4 (-2.35) HK5 (-2.23) HK7 (0.24) HK9 (-0.78) HK11 (-1.94) HK12 (-0.65) HK13 (-0.48) HK14 (-2.04) HK15 (-1.00) HK16 (-0.99) HK18 (-0.77) HK19 (-2.44) HK20 (-0.20) HK21 (-1.94) HK22 (0.03) HK24 (-0.75) HK27 (-2.45) HK28 (-0.21) HK29 (-0.47) HK31 (-0.18) HK33 (0.60) HK36 (-2.95) HK37 (-1.97) HK38 (-2.38) HK39 (-1.52) HK42 (-1.30) HK46 (-2.03) HK47 (-2.57) HK49 (-2.05) HK62 (-0.13) HK63 (0.25) HK64 (-0.39) HK67 (-0.78) HK84 (0.00) HK85 (-0.56) SF1 (-0.79) SF12 (-1.15) SF15 (-1.64) SF17 (0.55) SF18 (-1.40) SF21 (-0.18) SF22 (-0.69) SF23 (0.57) SF32 (0.52) SF34 (0.75) SF35 (-1.61) SF3 (-1.59) SF30 (-1.44) HK2 (-0.95) HK23 (-0.29) HK41 (-1.10) SF4 (0.17) SF8 (-2.30) SF9 (-2.41)