OncoDB.HCC Expression View

Gene name : UBE2L3
Ensembl ID ENSG00000185651
Description Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcH7) (E2-F1) (L-UBC). [Source:Uniprot/SWISSPROT;Acc:P68036]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
1 percent with 2 folds change ( 1 up and 0 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     Affy. Microarray - - Iizuka et al., J Cancer Res Clin Oncol 132:473 (2006)
Links Entrez Gene    
Display nearby genome region Chr 22 from 15251957 bp to 25308323 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 841188 -- IMAGE clone locate on exon ( tblastx )
841261 -- IMAGE clone locate on exon ( tblastx )
853988 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.39) HK1 (0.62) HK3 (0.55) HK4 (-0.00) HK5 (0.32) HK7 (0.73) HK9 (0.36) HK11 (0.41) HK12 (0.64) HK13 (0.50) HK14 (0.86) HK15 (1.16) HK16 (0.70) HK18 (-0.02) HK19 (0.75) HK20 (-0.35) HK21 (0.77) HK22 (-0.17) HK24 (0.37) HK27 (0.27) HK28 (-0.47) HK29 (0.53) HK31 (-0.78) HK33 (-0.15) HK36 (0.10) HK37 (0.01) HK38 (0.12) HK39 (0.54) HK42 (0.33) HK46 (0.85) HK47 (-0.61) HK49 (0.24) HK62 (-0.27) HK63 (0.18) HK64 (0.23) HK67 (0.48) HK84 (0.84) HK85 (0.15) SF1 (-0.76) SF12 (0.78) SF15 (-0.42) SF17 (0.78) SF18 (0.54) SF21 (0.19) SF22 (0.57) SF23 (0.30) SF32 (-0.14) SF34 (0.27) SF35 (-0.36) SF3 (0.36) SF30 (0.34) HK2 (-0.36) HK23 (0.37) HK41 (-0.23) SF4 (0.48) SF8 (0.27) SF9 (0.16)