OncoDB.HCC Expression View

Gene name : NRG3
Ensembl ID ENSG00000185737
Description Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)]. [Source:Uniprot/SWISSPROT;Acc:P56975]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
56 percent with 2 folds change ( 1 up and 13 down in 25 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 10 from 78624786 bp to 89736913 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 52754 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.00) HK3 (-1.71) HK4 (0.00) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (-0.57) HK12 (-3.07) HK13 (0.00) HK14 (-1.97) HK15 (-2.02) HK16 (-2.55) HK18 (-1.19) HK19 (0.64) HK20 (0.00) HK21 (0.10) HK22 (-0.56) HK24 (-1.15) HK27 (0.00) HK28 (-1.27) HK29 (0.00) HK31 (-0.84) HK33 (-0.64) HK36 (-0.58) HK37 (-1.32) HK38 (-1.21) HK39 (-1.62) HK42 (0.00) HK46 (-0.41) HK47 (0.00) HK49 (0.00) HK62 (0.23) HK63 (0.00) HK64 (0.00) HK67 (3.50) HK84 (0.00) HK85 (0.00) SF1 (0.00) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (-0.95) SF34 (0.00) SF35 (0.00) SF3 (0.00) SF30 (0.00) HK2 (0.00) HK23 (-4.84) HK41 (0.00) SF4 (-1.39) SF8 (0.00) SF9 (-0.34)