OncoDB.HCC Expression View

Gene name : IFITM1
Ensembl ID ENSG00000185885
Description Interferon-induced transmembrane protein 1 (Interferon-induced protein 17) (Interferon-inducible protein 9-27) (Leu-13 antigen) (CD225 antigen). [Source:Uniprot/SWISSPROT;Acc:P13164]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
40 percent with 2 folds change ( 3 up and 20 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     cDNA Microarray - - Delpuech et al., Oncogene 21:2926 (2002)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 11 from 0 bp to 5305272 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 509641 -- IMAGE clone locate on exon ( blastn )
755599 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.99) HK1 (0.19) HK3 (-1.17) HK4 (-2.06) HK5 (1.54) HK7 (-0.79) HK9 (-0.53) HK11 (-0.24) HK12 (0.36) HK13 (-1.26) HK14 (-0.99) HK15 (0.50) HK16 (0.74) HK18 (-1.21) HK19 (-1.16) HK20 (-0.72) HK21 (-0.24) HK22 (-0.38) HK24 (-0.84) HK27 (0.26) HK28 (-1.33) HK29 (-0.52) HK31 (-0.77) HK33 (-0.31) HK36 (-1.23) HK37 (-1.22) HK38 (1.51) HK39 (-0.39) HK42 (-2.03) HK46 (-1.33) HK47 (-1.67) HK49 (0.40) HK62 (-0.17) HK63 (-2.50) HK64 (-2.20) HK67 (-1.26) HK84 (-0.55) HK85 (-1.71) SF1 (0.06) SF12 (-1.17) SF15 (0.29) SF17 (0.20) SF18 (1.71) SF21 (0.99) SF22 (0.42) SF23 (-0.20) SF32 (-0.36) SF34 (0.32) SF35 (0.13) SF3 (-1.04) SF30 (0.77) HK2 (-0.97) HK23 (-1.14) HK41 (-1.19) SF4 (0.49) SF8 (0.18) SF9 (-0.57)