OncoDB.HCC Expression View

Gene name : ACADSB
Ensembl ID ENSG00000196177
Description Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial precursor (EC 1.3.99.-) (SBCAD) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase). [Source:Uniprot/SWISSPROT;Acc:P45954]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
52 percent with 2 folds change ( 1 up and 29 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Affy. Microarray - - Iizuka et al., J Cancer Res Clin Oncol 132:473 (2006)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Liang et al., Proteomics 5:2258 (2005)
down     Proteomic Analysis - - Blanc et al., Proteomics 5:37788 (2005)
Links Entrez Gene    
Display nearby genome region Chr 10 from 119758522 bp to 129807817 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 143209 -- IMAGE clone locate on exon ( blastn )
1076495 -- IMAGE clone locate on exon ( blastn )
82869 -- IMAGE clone locate on exon ( tblastx )
202209 -- IMAGE clone locate on exon ( tblastx )
243100 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.18) HK1 (-1.50) HK3 (-0.65) HK4 (-1.65) HK5 (-1.87) HK7 (-1.89) HK9 (-1.38) HK11 (-1.28) HK12 (-0.39) HK13 (-0.80) HK14 (-1.49) HK15 (-1.21) HK16 (-1.08) HK18 (-0.68) HK19 (-0.92) HK20 (-1.49) HK21 (-1.55) HK22 (-0.41) HK24 (-1.15) HK27 (-1.03) HK28 (-1.06) HK29 (-1.11) HK31 (-0.06) HK33 (0.32) HK36 (-0.84) HK37 (-0.30) HK38 (-0.78) HK39 (-1.89) HK42 (-1.57) HK46 (-0.67) HK47 (0.22) HK49 (-2.55) HK62 (-0.83) HK63 (0.15) HK64 (-1.06) HK67 (1.47) HK84 (-1.66) HK85 (-0.48) SF1 (-0.43) SF12 (-1.50) SF15 (-0.50) SF17 (0.16) SF18 (-0.56) SF21 (-1.77) SF22 (-1.04) SF23 (0.81) SF32 (-1.12) SF34 (-1.03) SF35 (-1.71) SF3 (-0.95) SF30 (-1.39) HK2 (-0.52) HK23 (-0.06) HK41 (-0.41) SF4 (-0.60) SF8 (-1.09) SF9 (-1.69)