OncoDB.HCC Expression View

Gene name : PPIA_HUMAN
Ensembl ID ENSG00000196262
Description Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein). [Source:Uniprot/SWISSPROT;Acc:P62937]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
24 percent with 2 folds change ( 13 up and 0 down in 53 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     Affy. Microarray - - Iizuka et al., J Cancer Res Clin Oncol 132:473 (2006)
up     Proteomic Analysis - - Li et al., Proteomics 5:1125 (2005)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 7 from 39802804 bp to 49809240 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 341834 -- IMAGE clone locate on exon ( blastn )
CH2 (0.00) HK1 (0.13) HK3 (1.09) HK4 (0.87) HK5 (0.37) HK7 (0.51) HK9 (0.25) HK11 (0.53) HK12 (0.56) HK13 (0.74) HK14 (1.18) HK15 (0.95) HK16 (0.90) HK18 (1.17) HK19 (0.46) HK20 (1.12) HK21 (0.75) HK22 (0.91) HK24 (1.01) HK27 (0.80) HK28 (0.26) HK29 (0.00) HK31 (-0.94) HK33 (1.16) HK36 (0.56) HK37 (0.63) HK38 (0.21) HK39 (-0.17) HK42 (0.93) HK46 (0.43) HK47 (1.28) HK49 (0.25) HK62 (-0.66) HK63 (0.08) HK64 (0.12) HK67 (0.38) HK84 (1.77) HK85 (0.05) SF1 (-0.95) SF12 (0.49) SF15 (0.69) SF17 (1.00) SF18 (1.61) SF21 (-0.91) SF22 (0.00) SF23 (0.48) SF32 (0.63) SF34 (0.00) SF35 (0.36) SF3 (0.33) SF30 (0.30) HK2 (1.22) HK23 (1.03) HK41 (2.32) SF4 (0.80) SF8 (0.45) SF9 (1.49)