OncoDB.HCC Expression View

Gene name : IGF2R
Ensembl ID ENSG00000197081
Description Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate [Source:Uniprot/SWISSPROT;Acc:P11717]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
12 percent with 2 folds change ( 7 up and 0 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- RT-PCR, Mutation, LOH    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 6 from 155310121 bp to 165447573 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 79712 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.02) HK1 (-0.91) HK3 (0.31) HK4 (0.61) HK5 (-0.32) HK7 (0.60) HK9 (0.47) HK11 (-0.03) HK12 (1.34) HK13 (0.95) HK14 (0.70) HK15 (0.77) HK16 (0.42) HK18 (0.75) HK19 (0.68) HK20 (0.79) HK21 (0.43) HK22 (0.81) HK24 (0.11) HK27 (0.65) HK28 (-0.54) HK29 (0.00) HK31 (1.35) HK33 (-0.52) HK36 (-0.54) HK37 (-0.22) HK38 (-0.54) HK39 (0.54) HK42 (-0.49) HK46 (0.69) HK47 (0.60) HK49 (0.32) HK62 (-0.91) HK63 (0.70) HK64 (1.71) HK67 (0.52) HK84 (0.47) HK85 (0.02) SF1 (0.86) SF12 (1.46) SF15 (-0.41) SF17 (-0.78) SF18 (-0.00) SF21 (-0.32) SF22 (-0.01) SF23 (-0.35) SF32 (0.39) SF34 (0.96) SF35 (-0.52) SF3 (1.31) SF30 (0.15) HK2 (0.72) HK23 (-0.09) HK41 (1.03) SF4 (0.22) SF8 (0.03) SF9 (0.27)