OncoDB.HCC Expression View

Gene name : GPAA1
Ensembl ID ENSG00000197858
Description Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1). [Source:Uniprot/SWISSPROT;Acc:O43292]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
32 percent with 2 folds change ( 18 up and 0 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR, Western, chr. amplification    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 8 from 140209512 bp to 146274826 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 810059 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.04) HK1 (0.60) HK3 (0.84) HK4 (0.75) HK5 (1.63) HK7 (3.01) HK9 (0.94) HK11 (1.42) HK12 (0.69) HK13 (1.06) HK14 (1.40) HK15 (1.29) HK16 (-0.17) HK18 (0.80) HK19 (0.21) HK20 (0.94) HK21 (0.47) HK22 (0.20) HK24 (0.50) HK27 (0.94) HK28 (-0.27) HK29 (1.25) HK31 (0.58) HK33 (0.58) HK36 (-0.26) HK37 (1.08) HK38 (1.29) HK39 (1.26) HK42 (0.25) HK46 (0.48) HK47 (-0.95) HK49 (0.85) HK62 (-0.07) HK63 (-0.22) HK64 (1.17) HK67 (0.21) HK84 (1.73) HK85 (0.60) SF1 (1.34) SF12 (1.31) SF15 (0.84) SF17 (0.91) SF18 (0.00) SF21 (0.77) SF22 (1.17) SF23 (-0.39) SF32 (0.91) SF34 (0.24) SF35 (0.48) SF3 (-0.53) SF30 (1.13) HK2 (0.24) HK23 (0.81) HK41 (0.63) SF4 (0.09) SF8 (1.38) SF9 (0.54)