OncoDB.HCC Expression View

Gene name : CYP2A7
Ensembl ID ENSG00000198077
Description Cytochrome P450 2A6 (EC 1.14.14.1) (CYPIIA6) (Coumarin 7-hydroxylase) (P450 IIA3) (CYP2A3) (P450(I)). [Source:Uniprot/SWISSPROT;Acc:P11509]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
74 percent with 2 folds change ( 8 up and 29 down in 50 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 19 from 41041286 bp to 51226008 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 85561 -- IMAGE clone locate on exon ( blastn )
CH2 (0.00) HK1 (-1.29) HK3 (-3.13) HK4 (1.17) HK5 (-0.70) HK7 (-1.01) HK9 (-0.01) HK11 (-2.03) HK12 (-3.08) HK13 (0.02) HK14 (-4.41) HK15 (-2.46) HK16 (1.18) HK18 (-1.52) HK19 (-3.51) HK20 (-2.34) HK21 (-1.73) HK22 (1.65) HK24 (0.20) HK27 (-3.21) HK28 (1.09) HK29 (0.45) HK31 (0.28) HK33 (2.61) HK36 (0.00) HK37 (-6.42) HK38 (-3.68) HK39 (-2.10) HK42 (-2.43) HK46 (-4.62) HK47 (0.00) HK49 (-1.82) HK62 (0.85) HK63 (-0.43) HK64 (-0.28) HK67 (0.00) HK84 (-3.97) HK85 (0.00) SF1 (1.28) SF12 (-3.42) SF15 (-3.75) SF17 (0.55) SF18 (-2.23) SF21 (0.00) SF22 (2.85) SF23 (0.00) SF32 (-0.92) SF34 (-1.55) SF35 (-2.50) SF3 (-0.59) SF30 (-2.23) HK2 (-2.26) HK23 (-2.73) HK41 (2.70) SF4 (-3.96) SF8 (-2.27) SF9 (-0.33)